Immune-awakening revealed by peripheral T cell dynamics after one cycle of immunotherapy

Our understanding of how checkpoint inhibitors (CPI) affect T cell evolution is incomplete, limiting our ability to achieve full clinical benefit from these drugs. Here we analyzed peripheral T cell populations after one cycle of CPI and identified a dynamic awakening of the immune system revealed b...

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Publicat a:Nat Cancer
Autors principals: Valpione, Sara, Galvani, Elena, Tweedy, Joshua, Mundra, Piyushkumar A., Banyard, Antonia, Middlehurst, Philippa, Barry, Jeff, Mills, Sarah, Salih, Zena, Weightman, John, Gupta, Avinash, Gremel, Gabriela, Baenke, Franziska, Dhomen, Nathalie, Lorigan, Paul C., Marais, Richard
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046489/
https://ncbi.nlm.nih.gov/pubmed/32110781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43018-019-0022-x
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