SPAG5‐AS1 inhibited autophagy and aggravated apoptosis of podocytes via SPAG5/AKT/mTOR pathway

OBJECTIVES: Podocyte injury is a prediction marker of diabetic nephropathy (DN), and AKT/mTOR pathway–mediated inhibition of autophagy is widely reported to contribute to podocyte damage. Recent study stated that sperm‐associated antigen 5 (SPAG5) activated AKT/mTOR signalling in bladder urothelial...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Prolif
Päätekijät: Xu, Jun, Deng, Yujie, Wang, Yi, Sun, Xiaofang, Chen, Shuqin, Fu, Guoxiang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2020
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046304/
https://ncbi.nlm.nih.gov/pubmed/31957155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12738
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