Proteolysis and cartilage development are activated in the synovium after surgical induction of post traumatic osteoarthritis

Anterior cruciate ligament (ACL) transection surgery in the minipig induces post-traumatic osteoarthritis (PTOA) in a pattern similar to that seen in human patients after ACL injury. Prior studies have reported the presence of cartilage matrix-degrading proteases, such as Matrix metalloproteinase-1...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ayturk, Ugur M., Sieker, Jakob T., Haslauer, Carla M., Proffen, Benedikt L., Weissenberger, Manuela H., Warman, Matthew L., Fleming, Braden C., Murray, Martha M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046188/
https://ncbi.nlm.nih.gov/pubmed/32107493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229449
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