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The effect of Apremilast on signal transduction and IL-10 production in CD39high regulatory B cells in patients with psoriatic arthritis

BACKGROUND. IL-10-producing regulatory B cells (Bregs) are of great importance in autoimmunity, as they inhibit proinflammatory T cells. We have shown that IL-10-producing Bregs in psoriatic arthritis(PsA) were decreased and inversely correlated with IFNγ+T cells (TH1 cells) and IL-17+ T cells (TH17...

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Detaylı Bibliyografya
Yayımlandı:Mediterr J Rheumatol
Asıl Yazarlar: Sakkas, Lazaros I., Mavropoulos, Athanasios, Zafiriou, Efterpi, Roussaki-Schulze, Aggeliki, Bogdanos, Dimitrios P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Mediterranean Journal of Rheumatology (MJR) 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7045954/
https://ncbi.nlm.nih.gov/pubmed/32185301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.31138/mjr.29.1.59
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