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Facile High Performance Liquid Chromatography Mass Spectrometry Method for Analysis of Cyclocreatine and Phosphocyclocreatine in Complex Mixtures of Amino Acids

Creatine transporter deficiency (CTD) is caused by a defect in the X-linked creatine transporter SLC6A8 gene leading to severe neurologic and physiologic conditions. Cyclocreatine and phosphocyclocreatine supplementation is seen as a potential treatment, but the presence of these compounds within co...

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Détails bibliographiques
Publié dans:J Agric Food Chem
Auteurs principaux: Tao, Dingyin, Leister, William, Huang, Wenwei, Alimardanov, Asaf, LeClair, Christopher A.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7045947/
https://ncbi.nlm.nih.gov/pubmed/31194545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jafc.9b01878
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