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Interferon targeted therapies in systemic lupus erythematosus

Type I interferons secreted by plasmacytoid dendritic cells (pDCs) play a crucial role in the pathogenesis of systemic lupus erythematosus by driving the formation of autoantibodies against nuclear debris. Inherited mutations causing activation of the Type I interferon pathway result in a phenotype...

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Detalhes bibliográficos
Publicado no:Mediterr J Rheumatol
Main Authors: Misra, Durga Prasanna, Negi, Vir Singh
Formato: Artigo
Idioma:Inglês
Publicado em: The Mediterranean Journal of Rheumatology (MJR) 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7045923/
https://ncbi.nlm.nih.gov/pubmed/32185249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.31138/mjr.28.1.13
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