Chemoenzymatic Halocyclization of 4-Pentenoic Acid at Preparative Scale

[Image: see text] The scale-up of chemoenzymatic bromolactonization to 100 g scale is presented, together with an identification of current limitations. The preparative-scale reaction also allowed for meaningful mass balances identifying current bottlenecks of the chemoenzymatic reaction.

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Publié dans:ACS Sustain Chem Eng
Auteurs principaux: Höfler, Georg T., But, Andrada, Younes, Sabry H. H., Wever, Ron, Paul, Caroline E., Arends, Isabel W. C. E., Hollmann, Frank
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2020
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7045808/
https://ncbi.nlm.nih.gov/pubmed/32117647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssuschemeng.9b07494
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