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Improved Synthesis and Isolation of Bedaquiline
[Image: see text] Bedaquiline (BDQ) is the most critical pharmaceutical in the world for treating multidrug-resistant Mycobacterium tuberculosis. Despite it being highly effective, BDQ asymmetric synthesis remains a challenge. Herein, the influence of chiral bases, namely, bis(1-phenylethyl)amine, b...
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| Publicado no: | ACS Omega |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2020
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7045498/ https://ncbi.nlm.nih.gov/pubmed/32118176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b04037 |
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