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Computational modeling of the effects of autophagy on amyloid-β peptide levels

BACKGROUND: Autophagy is an evolutionarily conserved intracellular process that is used for delivering proteins and organelles to the lysosome for degradation. For decades, autophagy has been speculated to regulate amyloid-β peptide (Aβ) accumulation, which is involved in Alzheimer’s disease (AD); h...

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Pubblicato in:Theor Biol Med Model
Autori principali: Han, Kyungreem, Kim, Soon Ho, Choi, MooYoung
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7045373/
https://ncbi.nlm.nih.gov/pubmed/32102666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12976-020-00119-6
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