CBX4 transcriptionally suppresses KLF6 via interaction with HDAC1 to exert oncogenic activities in clear cell renal cell carcinoma

BACKGROUND: Dysregulation of polycomb chromobox (CBX) proteins that mediate epigenetic gene silencing contributes to the progression of human cancers. Yet their roles in clear cell renal cell carcinoma (ccRCC) remain to be explored. METHODS: The expression of CBX4 and its clinical significance were...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Jiang, Nan, Niu, Gang, Pan, Ying-Hua, Pan, Wenwei, Zhang, Mei-Fang, Zhang, Chris Zhiyi, Shen, Huimin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044754/
https://ncbi.nlm.nih.gov/pubmed/32113161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102692
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