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Simultaneous Requirements for Hes1 in Retinal Neurogenesis and Optic Cup–Stalk Boundary Maintenance
The bHLH transcription factor Hes1 is a key downstream effector for the Notch signaling pathway. During embryogenesis neural progenitors express low levels of Hes1 in an oscillating pattern, whereas glial brain boundary regions (e.g., isthmus) have high, sustained Hes1 levels that suppress neuronal...
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| Publicado no: | J Neurosci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7044741/ https://ncbi.nlm.nih.gov/pubmed/31949107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2327-19.2020 |
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