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Neuronal Protein Tyrosine Phosphatase 1B Hastens Amyloid β-Associated Alzheimer's Disease in Mice

Alzheimer's disease (AD) is the most common neurodegenerative disorder, resulting in the progressive decline of cognitive function in patients. Familial forms of AD are tied to mutations in the amyloid precursor protein, but the cellular mechanisms that cause AD remain unclear. Inflammation and...

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Publicat a:J Neurosci
Autors principals: Ricke, Konrad M., Cruz, Shelly A., Qin, Zhaohong, Farrokhi, Kaveh, Sharmin, Fariba, Zhang, Li, Zasloff, Michael A., Stewart, Alexandre F.R., Chen, Hsiao-Huei
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044730/
https://ncbi.nlm.nih.gov/pubmed/31915254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2120-19.2019
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