Identification of a novel 1,2 oxazine that can induce apoptosis by targeting NF-κB in hepatocellular carcinoma cells

Constitutive activation of NF-κB is associated with proinflammatory diseases and suppression of the NF-κB signaling pathway has been considered as an effective therapeutic strategy in the treatment of various cancers including hepatocellular carcinoma (HCC). Herein, we report the synthesis of 1,2 ox...

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Veröffentlicht in:Biotechnol Rep (Amst)
Hauptverfasser: Somu, Chaithanya, Mohan, Chakrabhavi Dhananjaya, Ambekar, Sachin, Dukanya, Rangappa, Shobith, Baburajeev, CP, Sukhorukov, Alexey, Mishra, Srishti, Shanmugam, Muthu K, Chinnathambi, Arunachalam, Awad Alahmadi, Tahani, Alharbi, Sulaiman Ali, Basappa, Rangappa, Kanchugarakoppal S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044713/
https://ncbi.nlm.nih.gov/pubmed/32140443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.btre.2020.e00438
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