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Bioinformatics and computational approaches for analyzing patient-derived disease models in cancer research

Patient-derived organoids (PDO) and patient-derived xenografts (PDX) continue to emerge as important preclinical platforms for investigations into the molecular landscape of cancer. While the advantages and disadvantage of these models have been described in detail, this review focuses in particular...

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Pubblicato in:Comput Struct Biotechnol J
Autore principale: Gendoo, Deena M.A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Research Network of Computational and Structural Biotechnology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044647/
https://ncbi.nlm.nih.gov/pubmed/32128067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.01.010
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