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The absence of SOX2 in the anterior foregut alters the esophagus into trachea and bronchi in both epithelial and mesenchymal components

In the anterior foregut (AFG) of mouse embryos, the transcription factor SOX2 is expressed in the epithelia of the esophagus and proximal branches of respiratory organs comprising the trachea and bronchi, whereas NKX2.1 is expressed only in the epithelia of respiratory organs. Previous studies using...

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Dettagli Bibliografici
Pubblicato in:Biol Open
Autori principali: Teramoto, Machiko, Sugawara, Ryo, Minegishi, Katsura, Uchikawa, Masanori, Takemoto, Tatsuya, Kuroiwa, Atsushi, Ishii, Yasuo, Kondoh, Hisato
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044460/
https://ncbi.nlm.nih.gov/pubmed/31988094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.048728
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