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Haloperidol bound D(2) dopamine receptor structure inspired the discovery of subtype selective ligands
The D(2) dopamine receptor (DRD2) is one of the most well-established therapeutic targets for neuropsychiatric and endocrine disorders. Most clinically approved and investigational drugs that target this receptor are known to be subfamily-selective for all three D(2)-like receptors, rather than subt...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7044277/ https://ncbi.nlm.nih.gov/pubmed/32103023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14884-y |
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