Single-cell Transcriptome Mapping Identifies Common and Cell-type Specific Genes Affected by Acute Delta9-tetrahydrocannabinol in Humans

Delta-9-tetrahydrocannabinol (THC) is known to modulate immune response in peripheral blood cells. The mechanisms of THC’s effects on gene expression in human immune cells remains poorly understood. Combining a within-subject design with single cell transcriptome mapping, we report that THC acutely...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Hu, Ying, Ranganathan, Mohini, Shu, Chang, Liang, Xiaoyu, Ganesh, Suhas, Osafo-Addo, Awo, Yan, Chunhua, Zhang, Xinyu, Aouizerat, Bradley E., Krystal, John H., D’Souza, Deepak C., Xu, Ke
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044203/
https://ncbi.nlm.nih.gov/pubmed/32103029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59827-1
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