Lung CD4(+) resident memory T cells remodel epithelial responses to accelerate neutrophil recruitment during pneumonia

Previous pneumococcal experience establishes lung-resident IL-17A-producing CD4(+) memory T(RM) cells that accelerate neutrophil recruitment against heterotypic pneumococci. Herein, we unravel a novel crosstalk between CD4(+) T(RM) cells and lung epithelial cells underlying this protective immunity....

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Udgivet i:Mucosal Immunol
Main Authors: Shenoy, Anukul T., Wasserman, Gregory A., Arafa, Emad I., Wooten, Alicia K., Smith, Nicole M.S., Martin, Ian M.C., Jones, Matthew R., Quinton, Lee J., Mizgerd, Joseph P.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044037/
https://ncbi.nlm.nih.gov/pubmed/31748706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-019-0229-2
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