Predicting the Benefit of Adjuvant Aromatase Inhibitor Therapy in Postmenopausal Breast Cancer Patients with Phosphorylated S6K1 Expression Status

PURPOSE: Phosphorylated ribosomal S6 kinase 1 (pS6K1) is a major downstream regulator of the mammalian target of rapamycin (mTOR) pathway. Recent studies have addressed the role of S6K1 in adipogenesis. pS6K1 may affect the outcome of estrogen depletion therapy in patients with hormone-sensitive bre...

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Detalhes bibliográficos
Publicado no:J Breast Cancer
Main Authors: Choi, Jihye, Park, Chan Sub, Seong, Min-Ki, Seol, Hyesil, Kim, Jae-Sung, Park, In-Chul, Noh, Woo Chul, Kim, Hyun-Ah
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Breast Cancer Society 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043945/
https://ncbi.nlm.nih.gov/pubmed/32140266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4048/jbc.2020.23.e5
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