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Analysis of unusual and signature APOBEC-mutations in HIV-1 pol next-generation sequences
INTRODUCTION: At low mutation-detection thresholds, next generation sequencing (NGS) for HIV-1 genotypic resistance testing is susceptible to artifactual detection of mutations arising from PCR error and APOBEC-mediated G-to-A hypermutation. METHODS: We analyzed published HIV-1 pol Illumina NGS data...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7043932/ https://ncbi.nlm.nih.gov/pubmed/32102090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225352 |
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