Ciliary Rab28 and the BBSome negatively regulate extracellular vesicle shedding

Cilia both receive and send information, the latter in the form of extracellular vesicles (EVs). EVs are nano-communication devices that influence cell, tissue, and organism behavior. Mechanisms driving ciliary EV biogenesis are almost entirely unknown. Here, we show that the ciliary G-protein Rab28...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Akella, Jyothi S, Carter, Stephen P, Nguyen, Ken, Tsiropoulou, Sofia, Moran, Ailis L, Silva, Malan, Rizvi, Fatima, Kennedy, Breandan N, Hall, David H, Barr, Maureen M, Blacque, Oliver E
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2020
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043889/
https://ncbi.nlm.nih.gov/pubmed/32101165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50580
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