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Translational initiation in E. coli occurs at the correct sites genome-wide in the absence of mRNA-rRNA base-pairing

Shine-Dalgarno (SD) motifs are thought to play an important role in translational initiation in bacteria. Paradoxically, ribosome profiling studies in E. coli show no correlation between the strength of an mRNA’s SD motif and how efficiently it is translated. Performing profiling on ribosomes with a...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Saito, Kazuki, Green, Rachel, Buskirk, Allen R
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043885/
https://ncbi.nlm.nih.gov/pubmed/32065583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55002
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