A209 ROLE OF SEROTONIN-AUTOPHAGY AXIS IN REGULATION OF EPITHELIAL CELL FUNCTION AND MICROBIOTA COMPOSITION IN GUT

BACKGROUND: Serotonin (5-hydroxytryptamine; 5-HT), an enteric signalling molecule mainly produced by the enterochromaffin (EC) cells of the intestinal epithelium regulates various processes of the gut. Tryptophan hydroxylase 1 (Tph1) is the rate-limiting enzyme of 5-HT biosynthesis in EC cells. In i...

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Publicat a:J Can Assoc Gastroenterol
Autors principals: Haq, S, Wang, H, Kim, J J, Kwon, E Y, Banskota, S, Grondin, J, Hassan, N, Brumell, J, Philpott, D, Khan, W I
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Poster Presentation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043578/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwz047.208
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