Network Pharmacology-Based Prediction and Verification of Qingluo Tongbi Formula to Reduce Liver Toxicity of Tripterygium wilfordii via UGT2B7 in Endoplasmic Reticulum

BACKGROUND: The hepatotoxicity of Tripterygium wilfordii Hook. f. (TWHF) limits its clinic utilization. Qingluo Tongbi formula (QTF) was formulated based on a basic Chinese medicine theory. Previous studies have confirmed the safety and efficacy of QTF in treating rheumatoid arthritis. Therefore, we...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Li, Ming, Wang, Jing, Fu, Ling, Lu, Yan, Xu, Jianya, Zhou, Lingling, Zhu, Huaxu, Fang, Liang, Feng, Zhe, Xie, Tong, Zhou, Xueping
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2020
Assuntos:
Animal Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043354/
https://ncbi.nlm.nih.gov/pubmed/32061080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.920376
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