CCL2 and CXCL12 Derived from Mesenchymal Stromal Cells Cooperatively Polarize IL-10+ Tissue Macrophages to Mitigate Gut Injury

Mesenchymal stromal cell (MSC)-based therapy for inflammatory diseases involves paracrine and efferocytotic activation of immunosuppressive interleukin-10(+) (IL-10(+)) macrophages. The paracrine pathway for MSC-mediated IL-10(+) macrophage functionality and response to tissue injury is not fully un...

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Vydáno v:Cell Rep
Hlavní autoři: Giri, Jayeeta, Das, Rahul, Nylen, Emily, Chinnadurai, Raghavan, Galipeau, Jacques
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043065/
https://ncbi.nlm.nih.gov/pubmed/32049021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.01.047
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