Worldwide Secular Trends in Age at Pubertal Onset Assessed by Breast Development Among Girls: A Systematic Review and Meta-analysis

IMPORTANCE: The initial clinical sign of pubertal onset in girls is breast gland development (thelarche). Although numerous studies have used recalled age at menarche (first menstruation) to assess secular trends of pubertal timing, no systematic review has been conducted of secular trends of thelar...

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Detalhes bibliográficos
Publicado no:JAMA Pediatr
Main Authors: Eckert-Lind, Camilla, Busch, Alexander S., Petersen, Jørgen H., Biro, Frank M., Butler, Gary, Bräuner, Elvira V., Juul, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2020
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042934/
https://ncbi.nlm.nih.gov/pubmed/32040143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapediatrics.2019.5881
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