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Comparison of Tightly Controlled Dose Reduction of Biologics With Usual Care for Patients With Psoriasis: A Randomized Clinical Trial

IMPORTANCE: Biologics revolutionized the treatment of psoriasis. Biologics are given in a fixed dose, but lower doses might be possible. OBJECTIVE: To investigate whether dose reduction (DR) of biologics in patients with stable psoriasis is noninferior to usual care (UC). DESIGN, SETTING, AND PARTIC...

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Vydáno v:JAMA Dermatol
Hlavní autoři: Atalay, Selma, van den Reek, Juul M. P. A., den Broeder, Alfons A., van Vugt, Lieke J., Otero, Marisol E., Njoo, Marcellus D., Mommers, Johannes M., Ossenkoppele, Paul M., Koetsier, Marjolein I., Berends, Maartje A., van de Kerkhof, Peter C. M., Groenewoud, Hans M. M., Kievit, Wietske, de Jong, Elke M. G. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042801/
https://ncbi.nlm.nih.gov/pubmed/32049319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamadermatol.2019.4897
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