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Assessment of Duration and Effects of 3 vs 6 Months of Adjuvant Chemotherapy in High-Risk Stage II Colorectal Cancer: A Subgroup Analysis of the TOSCA Randomized Clinical Trial

IMPORTANCE: The addition of oxaliplatin to the standard 6-month fluorouracil-based adjuvant chemotherapy in stage II colorectal cancer has been reported to reduce the risk of relapse although it does not increase survival. The Three or Six Colon Adjuvant (TOSCA) trial compared 3 months with 6 months...

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Bibliografiske detaljer
Udgivet i:JAMA Oncol
Main Authors: Petrelli, Fausto, Labianca, Roberto, Zaniboni, Alberto, Lonardi, Sara, Galli, Fabio, Rulli, Eliana, Rosati, Gerardo, Corallo, Salvatore, Ronzoni, Monica, Cardellino, Giovanni Gerardo, Mattioli, Rodolfo, Mambrini, Andrea, Ciuffreda, Libero, Banzi, Maria, Pusceddu, Valeria, Maiello, Evaristo, Zampino, Maria, Zagonel, Vittorina, Marchetti, Paolo, Corsi, Domenico, Rimassa, Lorenza, Cinieri, Saverio, Sobrero, Alberto
Format: Artigo
Sprog:Inglês
Udgivet: American Medical Association 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042800/
https://ncbi.nlm.nih.gov/pubmed/32053133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2019.6486
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