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Orthologous promoters from related methylotrophic yeasts surpass expression of endogenous promoters of Pichia pastoris

Methylotrophic yeasts such as Komagataella phaffii (syn. Pichia pastoris, Pp), Hansenula polymorpha (Hp), Candida boidinii (Cb) and Pichia methanolica (Pm) are widely used protein production platforms. Typically, strong, tightly regulated promoters of genes coding for their methanol utilization (MUT...

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發表在:AMB Express
Main Authors: Vogl, Thomas, Fischer, Jasmin Elgin, Hyden, Patrick, Wasmayer, Richard, Sturmberger, Lukas, Glieder, Anton
格式: Artigo
語言:Inglês
出版: Springer Berlin Heidelberg 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042429/
https://ncbi.nlm.nih.gov/pubmed/32100120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-020-00972-1
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