Comparative Proteomics of Extended-Spectrum Cephalosporin-Resistant Neisseria gonorrhoeae Isolates Demonstrates Altered Protein Synthesis, Metabolism, Substance Transport, and Membrane Permeability

Neisseria gonorrhoeae isolates exhibit resistance to extended-spectrum cephalosporins (ESCs), the last remaining option for first-line empirical monotherapy. Here, we investigated the proteomic profiles of N. gonorrhoeae clinical isolates with ESC-resistance to support exploration of the antimicrobi...

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Gepubliceerd in:Front Microbiol
Hoofdauteurs: Diao, Nannan, Yan, Guoquan, Yang, Yang, Dong, Yuan, Wang, Ying, Gu, Weiming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
Onderwerpen:
Microbiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042406/
https://ncbi.nlm.nih.gov/pubmed/32140142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00169
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