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Dual-molecular barcode sequencing detects rare variants in tumor and cell free DNA in plasma
Conventional next generation sequencing analysis has provided important insights into cancer genetics. However, the detection of rare (low allele fraction) variants remains difficult because of the error-prone nucleotide changes derived from sequencing/PCR errors. To eliminate the false-positive var...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7042261/ https://ncbi.nlm.nih.gov/pubmed/32099048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60361-3 |
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