Glycation changes molecular organization and charge distribution in type I collagen fibrils

Collagen fibrils are central to the molecular organization of the extracellular matrix (ECM) and to defining the cellular microenvironment. Glycation of collagen fibrils is known to impact on cell adhesion and migration in the context of cancer and in model studies, glycation of collagen molecules h...

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Udgivet i:Sci Rep
Main Authors: Bansode, Sneha, Bashtanova, Uliana, Li, Rui, Clark, Jonathan, Müller, Karin H., Puszkarska, Anna, Goldberga, Ieva, Chetwood, Holly H., Reid, David G., Colwell, Lucy J., Skepper, Jeremy N., Shanahan, Catherine M., Schitter, Georg, Mesquida, Patrick, Duer, Melinda J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042214/
https://ncbi.nlm.nih.gov/pubmed/32099005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60250-9
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