DDOT: A Swiss Army Knife for Investigating Data-Driven Biological Ontologies

Systems biology requires not only genome-scale data but also methods to integrate these data into interpretable models. Previously, we developed approaches that organize omics data into a structured hierarchy of cellular components and pathways, called a “data-driven ontology.” Such hierarchies reca...

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Bibliografiske detaljer
Udgivet i:Cell Syst
Main Authors: Yu, Michael Ku, Ma, Jianzhu, Ono, Keiichiro, Zheng, Fan, Fong, Samson H., Gary, Aaron, Chen, Jing, Demchak, Barry, Pratt, Dexter, Ideker, Trey
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042149/
https://ncbi.nlm.nih.gov/pubmed/30878356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2019.02.003
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