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Principles of self-organization and load adaptation by the actin cytoskeleton during clathrin-mediated endocytosis
Force generation by actin assembly shapes cellular membranes. An experimentally constrained multiscale model shows that a minimal branched actin network is sufficient to internalize endocytic pits against membrane tension. Around 200 activated Arp2/3 complexes are required for robust internalization...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7041948/ https://ncbi.nlm.nih.gov/pubmed/31951196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49840 |
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