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Exploiting epigenetics for the treatment of inborn errors of metabolism

Gene therapy is currently considered as the optimal treatment for inborn errors of metabolism (IEMs), as it aims to permanently compensate for the primary genetic defect. However, emerging gene editing approaches such as CRISPR‐Cas9, in which the DNA of the host organism is edited at a precise locat...

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Dades bibliogràfiques
Publicat a:J Inherit Metab Dis
Autors principals: Rutten, Martijn G. S., Rots, Marianne G., Oosterveer, Maaike H.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041640/
https://ncbi.nlm.nih.gov/pubmed/30916397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jimd.12093
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