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Pre- and post-sequencing recommendations for functional annotation of human fecal metagenomes

BACKGROUND: Shotgun metagenomes are often assembled prior to annotation of genes which biases the functional capacity of a community towards its most abundant members. For an unbiased assessment of community function, short reads need to be mapped directly to a gene or protein database. The ability...

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Vydáno v:BMC Bioinformatics
Hlavní autoři: Treiber, Michelle L., Taft, Diana H., Korf, Ian, Mills, David A., Lemay, Danielle G.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041091/
https://ncbi.nlm.nih.gov/pubmed/32093654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3416-y
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