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重组甲硫氨酸酶调控PI3K/Akt/Glut-1通路抑制有氧糖酵解促进胃癌细胞凋亡

OBJECTIVE: To investigate the molecular mechanism of recombinant methioninase (rMETase) in promoting apoptosis of gastric cancer cells. METHODS: Gastric cancer SGC-7901 cells were treated with rMETase (final concentration of 1.25 and 2.50 mmmol/L) for 72 h, and the changes in the cell viability were...

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Bibliographic Details
Published in:Nan Fang Yi Ke Da Xue Xue Bao
Format: Artigo
Language:Inglês
Published: 南方医科大学学报编辑部 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7040764/
https://ncbi.nlm.nih.gov/pubmed/32376548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12122/j.issn.1673-4254.2020.01.05
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