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Estrogen accelerates heart regeneration by promoting the inflammatory response in zebrafish

Sexual differences have been observed in the onset and prognosis of human cardiovascular diseases, but the underlying mechanisms are not clear. Here, we found that zebrafish heart regeneration is faster in females, can be accelerated by estrogen and is suppressed by the estrogen-antagonist tamoxifen...

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Detalhes bibliográficos
Publicado no:J Endocrinol
Main Authors: Xu, Shisan, Xie, Fangjing, Tian, Li, Fallah, Samane, Babaei, Fatemeh, Manno, Sinai H C, Manno, Francis A M, Zhu, Lina, Wong, Kin Fung, Liang, Yimin, Ramalingam, Rajkumar, Sun, Lei, Wang, Xin, Plumb, Robert, Gethings, Lee, Lam, Yun Wah, Cheng, Shuk Han
Formato: Artigo
Idioma:Inglês
Publicado em: Bioscientifica Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7040496/
https://ncbi.nlm.nih.gov/pubmed/31977314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-19-0413
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