Anthralin Suppresses the Proliferation of Influenza Virus by Inhibiting the Cap-Binding and Endonuclease Activity of Viral RNA Polymerase

Influenza virus RNA-dependent RNA polymerase (vRdRp) does not have capping activity and relies on the capped RNAs produced by the host RNA polymerase II (RNAPII). The viral polymerases process the capped RNAs to produce short capped RNA fragments that are used as primers to initiate the transcriptio...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Hu, Ao, Li, Jing, Tang, Wei, Liu, Ge, Zhang, Haiwei, Liu, Chunlan, Chen, Xulin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7040080/
https://ncbi.nlm.nih.gov/pubmed/32132985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00178
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