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Innate T-αβ lymphocytes as new immunological components of anti-tumoral “off-target” effects of the tyrosine kinase inhibitor dasatinib

Kinase inhibitors hold great potential as targeted therapy against malignant cells. Among them, the tyrosine kinase inhibitor dasatinib is known for a number of clinically relevant off-target actions, attributed in part to effects on components of the immune system, especially conventional T-cells a...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Barbarin, Alice, Abdallah, Myriam, Lefèvre, Lucie, Piccirilli, Nathalie, Cayssials, Emilie, Roy, Lydia, Gombert, Jean-Marc, Herbelin, André
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039999/
https://ncbi.nlm.nih.gov/pubmed/32094501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60195-z
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