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A novelty-retrieval-extinction paradigm leads to persistent attenuation of remote fear memories

Exposure to a novel environment can enhance the extinction of recent contextual fear in mice. This has been explained by a tagging and capture hypothesis. Consistently, we show in mice that exposure to a novel environment before extinction training promoted the extinction of recent auditory fear. Ho...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Huang, Fulian, Zou, Guangjing, Li, Can, Meng, Hui, Liu, Xiaoyan, Yang, Zehua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039928/
https://ncbi.nlm.nih.gov/pubmed/32094477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60176-2
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