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CNS organoids: an innovative tool for neurological disease modeling and drug neurotoxicity screening
The paradigm of central nervous system (CNS) drug discovery has mostly relied on traditional approaches of rodent models or cell-based in vitro models. Owing to the issues of species differences between humans and rodents, it is difficult to correlate the robustness of data for neurodevelopmental st...
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| Gepubliceerd in: | Drug Discov Today |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7039749/ https://ncbi.nlm.nih.gov/pubmed/31783130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2019.11.010 |
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