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COTI-2 induces cell apoptosis in pediatric acute lymphoblastic leukemia via upregulation of miR-203

COTI-2 is a third-generation thiosemicarbazone, which is effective against a diverse group of human cancer cell lines at nanomolar concentrations. COTI-2 also showed superior activity against tumor cells, in vitro and in vivo. As a high efficacy and low toxicity agent, it currently candidates in a p...

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Bibliografische gegevens
Gepubliceerd in:Bioengineered
Hoofdauteurs: Guo, Yingmeng, Zhu, Xia, Sun, Xuerong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039633/
https://ncbi.nlm.nih.gov/pubmed/32063077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2020.1729927
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