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The topology of the ER-resident phospholipid methyltransferase Opi3 of Saccharomyces cerevisiae is consistent with in trans catalysis

Phospholipid N-methyltransferases (PLMTs) synthesize phosphatidylcholine by methylating phosphatidylethanolamine using S-adenosylmethionine as a methyl donor. Eukaryotic PLMTs are integral membrane enzymes located in the endoplasmic reticulum (ER). Recently Opi3, a PLMT of the yeast Saccharomyces ce...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Pawlik, Grzegorz, Renne, Mike F., Kol, Matthijs A., de Kroon, Anton I. P. M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039565/
https://ncbi.nlm.nih.gov/pubmed/31932304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011102
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