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Optimizing peptide nucleic acid probes for hybridization-based detection and identification of bacterial pathogens

Point-of-care (POC) diagnostics for infectious diseases have the potential to improve patient care and antibiotic stewardship. Nucleic acid hybridization is at the core of many amplification-free molecular diagnostics and detection probe configuration is key to diagnostic performance. Modified nucle...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Analyst
Hauptverfasser: Mach, Kathleen E., Kaushik, Aniruddha M., Hsieh, Kuangwen, Wong, Pak Kin, Wang, Tza-Huei, Liao, Joseph C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039532/
https://ncbi.nlm.nih.gov/pubmed/30656297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8an02194e
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