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A functional polymorphism in the ABCB1 transporter predicts pharmacologic response to combination of nortriptyline and morphine in neuropathic pain patients

Many genetic markers have been associated with variations in treatment response to analgesics, but none have been assessed in the context of combination therapies. In this study, the treatment effects of nortriptyline and morphine were tested for association with genetic markers relevant to pain pat...

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Detalhes bibliográficos
Publicado no:Pain
Main Authors: Benavides, Rodrigo, Vsevolozhskaya, Olga, Cattaneo, Stefano, Zaykin, Dmitri, Brenton, Ashley, Parisien, Marc, Verma, Vivek, Khoury, Samar, Gilron, Ian, Diatchenko, Luda
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039325/
https://ncbi.nlm.nih.gov/pubmed/31738228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001750
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