ALK Rearrangement Adenocarcinoma with Histological Transformation to Squamous Cell Carcinoma Resistant to Alectinib and Ceritinib

Specific tyrosine-kinase inhibitors (TKIs) are widely used for the treatment of non-small-cell lung cancers with anaplastic lymphoma kinase (ALK) translocations. However, most treated patients eventually develop resistance to the TKIs. The histological transformation into small cell carcinoma is wel...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Kaiho, Taisuke, Nakajima, Takahiro, Iwasawa, Shunichiro, Yonemori, Yoko, Yoshino, Ichiro
Format: Artigo
Language:Inglês
Published: Dove 2020
Subjects:
Case Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039243/
https://ncbi.nlm.nih.gov/pubmed/32110052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S236706
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