Surgical microscope with integrated fluorescence lifetime imaging for 5-aminolevulinic acid fluorescence-guided neurosurgery

Significance: 5-Aminolevulinic acid (5-ALA)-based fluorescence guidance in conventional neurosurgical microscopes is limited to strongly fluorescent tumor tissue. Therefore, more sensitive, intrasurgical 5-ALA fluorescence visualization is needed. Aim: Macroscopic fluorescence lifetime imaging (FLIM...

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Detalhes bibliográficos
Publicado no:J Biomed Opt
Main Authors: Erkkilä, Mikael T., Reichert, David, Hecker-Denschlag, Nancy, Wilzbach, Marco, Hauger, Christoph, Leitgeb, Rainer A., Gesperger, Johanna, Kiesel, Barbara, Roetzer, Thomas, Widhalm, Georg, Drexler, Wolfgang, Unterhuber, Angelika, Andreana, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Photo-Optical Instrumentation Engineers 2020
Assuntos:
Special Section on Selected Topics in Biophotonics: Fluorescence Lifetime Imaging and Optical Micromechanics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039165/
https://ncbi.nlm.nih.gov/pubmed/32096368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.25.7.071202
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