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THBS2, a microRNA-744-5p target, modulates MMP9 expression through CUX1 in pancreatic neuroendocrine tumors

The underlying molecular mechanisms of pancreatic neuroendocrine tumor (pNET) development have not yet been clearly identified. The present study revealed that thrombospondin 2 (THBS2) was downregulated in pNET tissues and cells. Forced expression of THBS2 inhibited the proliferation and migration o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncol Lett
Hauptverfasser: Jiao, Heng, Zeng, Lingxiao, Zhang, Jianpeng, Yang, Shengsheng, Lou, Wenhui
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039111/
https://ncbi.nlm.nih.gov/pubmed/32194660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.11273
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