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A Traction Force Threshold Signifies Metastatic Phenotypic Change in Multicellular Epithelia

Cancer metastasis has be en believed as a genetically programmed process that is commonly marked by biochemical signals. Here using extracellular matrix control of cellular mechanics, we establish that cellular force threshold can also mark in vitro metastatic phenotypic change and malignant transfo...

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Bibliographische Detailangaben
Veröffentlicht in:Soft Matter
Hauptverfasser: Zhang, Yao, Shi, Xuechen, Zhao, Tiankai, Huang, Changjin, Wei, Qiong, Tang, Xin, Santy, Lorraine, Saif, Taher M. A., Zhang, Sulin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039046/
https://ncbi.nlm.nih.gov/pubmed/31475279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sm00733d
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